A building in Manhattan's East Village has reportedly collapsed following a large explosion. Hundreds of fire firefighters are reportedly at the scene, battling what's become a seven-alarm blaze. The New York Post is reporting that as many as 30 people are missing while the New York Daily News reports that at least six people—including two firefighters—have been injured, one critically.

UPDATE 11:07 pm: Video of the actual explosion:

UPDATE 5:47 pm: Mayor Bill de Blasio says the explosion appears to have been caused by a gas leak.

UPDATE 4:43 pm: At least 12 people were injured in the collapse, according to CBS News. Three of those injuries are reportedly critical.

"We heard a big sound, then three or four people fell on the street," one witness told Reuters. "People were running and screaming."

UPDATE 4:20 pm: CBS New York is reporting that two people are in critical condition following the explosion.

A photo, via Google Maps, of the building at 125 2nd Ave. before the explosion:

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